Human Stromal Cell-Derived Factor-1 alpha (SDF-1α / CXCL12)
Stromal Cell Derived Factor-1 alpha (SDF-1α), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1α signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human and mouse SDF-1α share 99% sequence identity. Recombinant human SDF-1 alpha is a non-glycosylated protein, containing 68 amino acids and having a molecular mass of 8 kDa.
Ships ambient. Store frozen at -20 to -10C.
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